DMPK

This is a growing collection of content supporting DMPK and ADME laboratories with in Pharmaceutical, Biopharmaceutical and Contract Research Organizations.

It provides support for all the common assays including:

All use a consistent Binder Design and have matching BioRails DM Workflows with BioRails PTO Queues for requesting.

These binders have been created in collaboration with contract research organizations including Evotec.

High quality data and graphics ready for reporting to project teams or sending to CRO clients in multiple formats.

Contact us to arrange a demonstration today

Webinars

Best viewed in HD1080

 

In vitro Drug Metabolism

In vivo Pharmacokinetics

Demonstration Videos

These demonstration videos show how the combination of BioRails PTO and BioRails DM (which includes Morphit) can be used to
  • Request DMPK assays
  • Schedule experimentation
  • Execute DMPK protocols generating high quality data

Permeability

CACO-2

Binding

Brain Binding

Plasma Binding

Pharmacokinetics

IV Rat Bolus Study

Stability

Microsomal Stability

Hepatocyte Stability (Hepatocyte Clearance)

Plasma Stability

Distribution

Blood Brain Ratio

 

Interaction

CYP P450 Inhibition

CYP P450 IC50





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